Enantioselective Trifluoromethylthiolating Lactonization Catalyzed by an Indane-Based Chiral Sulfide
Congratulations! The first publication of our group in Angew. Chem. Int. Ed, "" has been published recently (Xiang Liu, Rui An, Xuelin Zhang, Jie Luo, and Xiaodan Zhao* Angew. Chem. Int. Ed. 2016, 55, 5846–5850).
An efficient approach for enantioselective trifluoromethylthiolating lactonization entails the use of an indane-based bifunctional chiral sulfide catalyst and a new shelf-stable electrophilic SCF3 reagent. This transformation represents the first enantioselective trifluoromethylthiolation that is enabled by a catalyst with a Lewis basic sulfur center.
This research was rated as the inside back cover.
Previous page: Organoselenium-Catalyzed Synthesis of Oxygen- and Nitrogen-Containing Heterocycles
Next page: Prof. Zucai Suo Visited Our Group